As tablets comprise a significant proportion of oral solid dosage forms, tools able to support in formulation and manufacturing efficiencies are of critical importance. Tablet compression is a science and an art, and a successful product run depends on a host of factors. Firstly a good formulation secondly process optimization strongly affect final quality of the tablet: how to choose properly the most suitable result depends completely on scientist and formulator’s decision. Mass uniformity, tensile strength, thickness, friability are ones of the most known parameters and values that have production needs, pharmacokinetics and pharmacodynamic specific and regulatory requirements. The presentation will present IMAGO, IMA Active division application to use the PI System to analyse the relationships between process parameters on the tablet press and determine optimal settings based on current asset performance, highlighting the advantages that this application brings in tablet production